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- visitors Metabolic network analysis of Streptomyces tenebrarius, a Streptomyces species with an active Entner-Doudoroff pathway nih.gov [HTML]I Borodina, C Scholler, A Eliasson, J … - Applied and …, 2005 - Am Soc Microbiol http //scholar.google.com/scholar?q=related vbWz9Ak9HjwJ scholar.google.com/ hl=ja as_sdt=2000 Streptomyces tenebrarius is an industrially important microorganism, producing an antibiotic complex that mainly consists of the aminoglycosides apramycin, tobramycin carbamate, and kanamycin B carbamate. When S. tenebrarius is used for industrial tobramycin ... Genome-scale reconstruction and in silico analysis of the Clostridium acetobutylicum ATCC 824 metabolic network J Lee, H Yun, AM Feist, BØ Palsson, SY Lee - Applied microbiology and …, 2008 - Springer http //scholar.google.com/scholar?q=related 6k93cgR0CzwJ scholar.google.com/ hl=ja as_sdt=2000 Page 1. GENOMICS AND PROTEOMICS Genome-scale reconstruction and in silico analysis of the Clostridium acetobutylicum ATCC 824 metabolic network Joungmin Lee Hongseok Yun Adam M. Feist Bernhard Ø. Palsson Sang Yup Lee ... Metabolic networks in motion 13C-based flux analysis nih.gov [HTML]U Sauer - Molecular systems biology, 2006 - nature.com http //scholar.google.com/scholar?q=related B0vTesydGZwJ scholar.google.com/ hl=ja as_sdt=2000 ... Curr Opin Biotechnol 16 350–355 | Article | PubMed | ISI | ChemPort |; Borodina I, Schöller C, Eliasson A, Nielsen J (2005) Metabolic network analysis of Streptomyces tenebrarius, a Streptomyces species with an active Entner–Doudoroff pathway. ... Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks hindawi.com [PDF]O Fiehn - Comparative and Functional Genomics, 2001 - Wiley Online Library http //scholar.google.com/scholar?q=related -r0O-RbpfxsJ scholar.google.com/ hl=ja as_sdt=2000 ... Metabolomics. The obvious next step in metabolic network analysis is to try to determine metabolic snapshots in a broad and comprehensive way. ... 13 Christensen B, Nielsen J. Metabolic network analysis a powerful tool in metabolic engineering. ... A metabolic network analysis NMR experiment design tool with user interface-driven model construction for depth-first search analysis T Zhu, C Phalakornkule, S Ghosh, IE Grossmann, … - Metabolic …, 2003 - Elsevier http //scholar.google.com/scholar?q=related Ov3p-3IVXxsJ scholar.google.com/ hl=ja as_sdt=2000 A Windows program for metabolic engineering analysis and experimental design has been developed. A graphical user interface enables the pictorial, “on-screen” construction of a metabolic network. Once a model is composed, balance equations are automatically generated. ... Genome-scale reconstruction and analysis of the Pseudomonas putida KT2440 metabolic network facilitates applications in biotechnology plos.org [HTML]J Puchałka, MA Oberhardt, M Godinho, A Bielecka, … - PLoS Comput …, 2008 - dx.plos.org PLoS Computational Biology is an open-access. http //scholar.google.com/scholar?q=related V6wktboEeLMJ scholar.google.com/ hl=ja as_sdt=2000 Integrated analysis of regulatory and metabolic networks reveals novel regulatory mechanisms in Saccharomyces cerevisiae cshlp.org [HTML]MJ Herrgård, BS Lee, V Portnoy, BØ … - Genome research, 2006 - genome.cshlp.org http //scholar.google.com/scholar?q=related -IQUN4gFKUgJ scholar.google.com/ hl=ja as_sdt=2000 ... biomass composition). The integration of the metabolic network analysis and the transcriptional regulatory network model described above is accomplished using the regulated flux balance analysis approach (Covert et al. 2001). In ... Validation of a metabolic network for Saccharomyces cerevisiae using mixed substrate studies ulaval.ca [PDF]PA Vanrolleghem, P de Jong-Gubbels, … - Biotechnology …, 1996 - interscience.wiley.com http //scholar.google.com/scholar?q=related jaCs_pUlSXcJ scholar.google.com/ hl=ja as_sdt=2000 Page 1. ARTICLES Validation of a Metabolic Network for Saccharomyces cerevisiae Using Mixed Substrate Studies Peter A. Vanrolleghem,*,† Patricia de Jong-Gubbels,‡ Walter M. van Gulik,§ Jack T. Pronk,‡ Johannes P. van Dijken,‡ and Sef Heijnen† ... Metabolic‐flux analysis of Saccharomyces cerevisiae CEN. PK113‐7D based on mass isotopomer measurements of 13C‐labeled primary metabolites WA Winden, JC Dam, C Ras, RJ Kleijn, JL … - FEMS yeast …, 2005 - Wiley Online Library Skip to Main Content. ... http //scholar.google.com/scholar?q=related fM6Xi9-F_GIJ scholar.google.com/ hl=ja as_sdt=2000 The efficiency of multi-target drugs the network approach might help drug design arxiv.org [PDF]P Csermely, V Agoston, S Pongor - Trends in pharmacological sciences, 2005 - Elsevier http //scholar.google.com/scholar?q=related U0rlpj3tgrYJ scholar.google.com/ hl=ja as_sdt=2000 ... 6111–6121. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (53). 8 B. Papp et al., Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast, Nature 429 (2004), pp. 661–664. Full Text via CrossRef | View Record in Scopus |.
https://w.atwiki.jp/metalmetabo/pages/28.html
- visitors Application of regulatory sequence analysis and metabolic network analysis to the interpretation of gene expression data psu.edu [PDF]J Van Helden, D Gilbert, L Wernisch, M Schroeder, … - Computational …, 2001 - Springer http //scholar.google.com/scholar?q=related JS_4j3CP5nEJ scholar.google.com/ hl=ja as_sdt=2000 Comparative metabolic network analysis of two xylose fermenting recombinant Saccharomyces cerevisiae strains T Grotkjær, P Christakopoulos, J Nielsen, L … - Metabolic Engineering, 2005 - Elsevier http //scholar.google.com/scholar?q=related m6nOh8HQbaIJ scholar.google.com/ hl=ja as_sdt=2000 The recombinant xylose fermenting strain Saccharomyces cerevisiae TMB3001 can grow on xylose, but the xylose utilisation rate is low. One important reason for the inefficient fermentation of xylose to ethanol is believed to be the imbalance of redox co-factors. In the present ... The Edinburgh human metabolic network reconstruction and its functional analysis nih.gov [HTML]H Ma, A Sorokin, A Mazein, A Selkov, E … - Molecular systems …, 2007 - nature.com http //scholar.google.com/scholar?q=related pgWLepUKeS0J scholar.google.com/ hl=ja as_sdt=2000 ... A main objective of human metabolic network analysis is to see how it is related with human disease. More than 10 000 human genes (half of the whole genome) have been reported to be related with one or more human diseases in the OMIM database (Hamosh et al, 2005). ... Reconstruction of metabolic networks from genome data and analysis of their global structure for various organisms oxfordjournals.org [PDF]H Ma, AP Zeng - Bioinformatics, 2003 - Oxford Univ Press http //scholar.google.com/scholar?q=related SuHZgSLeNw8J scholar.google.com/ hl=ja as_sdt=2000 ... It is one of the main tasks of metabolic network analysis to find possible conversion pathways between two metabolites. There may be many different pathways between two metabolites, among them the shortest pathway is of particular interest for network analysis. ... Metabolic network analysis of an adipoyl-7-ADCA-producing strain of Penicillium chrysogenum elucidation of adipate degradation J Thykaer, B Christensen, J Nielsen - Metabolic Engineering, 2002 - Elsevier http //scholar.google.com/scholar?q=related gycTvJYwT9kJ scholar.google.com/ hl=ja as_sdt=2000 An adipoyl-7-ADCA-producing, recombinant strain of Penicillium chrysogenum was characterized by metabolic network analysis, with special focus on the degradation of adipate and determination of the metabolic fluxes. Degradation of the side-chain precursor, adipate, causes an ... Potential metabolic limitations in lysine production by Corynebacterium glutamicum as revealed by metabolic network analysis JA Hollander - Applied Microbiology and Biotechnology, 1994 - Springer http //scholar.google.com/scholar?q=related BwIeARCnafMJ scholar.google.com/ hl=ja as_sdt=2000 Corynebacterium glutamicum and closely related Brevi- bacterium species are the most important organisms used for the industrial fermentative production of ly- sine. Although wild-type strains do not excrete lysine at all, classical mutation programs have resulted in strains ... Metabolic flux and metabolic network analysis of Penicillium chrysogenum using 2D [13C, 1H] COSY NMR measurements and cumulative bondomer simulation WA van Winden, WM van Gulik, D … - Biotechnology and …, 2003 - Wiley Online Library http //scholar.google.com/scholar?q=related Jy6SBrqyeHAJ scholar.google.com/ hl=ja as_sdt=2000 Abstract At present two alternative methods are avail- able for analyzing the fluxes in a metabolic network (1) combining measurements of net conversion rates with a set of metabolite balances including the cofactor bal- ances, or (2) leaving out the cofactor balances and fitting the ... Metabolic‐flux and network analysis in fourteen hemiascomycetous yeasts LM Blank, F Lehmbeck, U Sauer - FEMS yeast research, 2005 - Wiley Online Library http //scholar.google.com/scholar?q=related ILl2ugZn3ZcJ scholar.google.com/ hl=ja as_sdt=2000 ... (5). Oxaloacetate14 mit was estimated using Eq. (6)[16] (6). 2.6Metabolic-network analysis. We used a previously constructed metabolic network [1,24], which consists of the PP pathway, glycolysis, TCA cycle, gluconeogenesis, malic enzyme and by-product formation reactions. ... 13C metabolic flux analysis W Wiechert - Metabolic Engineering, 2001 - Elsevier http //scholar.google.com/scholar?q=related Eat1pl-yJGQJ scholar.google.com/ hl=ja as_sdt=2000 ... 6. B. Christensen and J. Nielsen, Metabolic network analysis, a powerful tool in metabolic engineering. Adv. Biochem. Eng. ... 209–231. 7. B. Christensen and J. Nielsen, Metabolic network analysis of Penicillium chrysogenum using 13 C-labeled glucose. Biotechnol. Bioeng. ... Multiple knockout analysis of genetic robustness in the yeast metabolic network tau.ac.il [PDF]D Deutscher, I Meilijson, M Kupiec, E Ruppin - Nature genetics, 2006 - nature.com http //scholar.google.com/scholar?q=related X5cH6RUwUF0J scholar.google.com/ hl=ja as_sdt=2000 ... | PubMed |; Kitano, H. Biological robustness. Nat. Rev. Genet. 5, 826–837 (2004). | Article | PubMed | ISI | ChemPort |; Papp, B. , Pál, C. Hurst, LD Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast. Nature 429, 661–664 (2004). ...
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- visitors Genome-scale reconstruction of the metabolic network in Staphylococcus aureus N 315 an initial draft to the two-dimensional annotation biomedcentral.com [HTML]SA Becker, BØ Palsson - BMC microbiology, 2005 - biomedcentral.com http //scholar.google.com/scholar?q=related 829ZIciJNnkJ scholar.google.com/ hl=ja as_sdt=2000 ... J Biol Chem 2004, 279 39532-39540. PubMed Abstract | Publisher Full Text OpenURL. Papp B, Pal C, Hurst LD Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast. Nature 2004, 429 661-664. ... Adaptive evolution of bacterial metabolic networks by horizontal gene transfer linkgroup.hu [PDF]C Pál, B Papp, MJ Lercher - Nature Genetics, 2005 - nature.com http //scholar.google.com/scholar?q=related j65eRY_pFyIJ scholar.google.com/ hl=ja as_sdt=2000 ... were present. Gene families with more than one member in E. coli K-12 were excluded from the analysis. Metabolic network analysis. We examined the reconstructed metabolic network (iJR904 GSM/GPR) of E. coli K-12. We ... Network analysis of metabolic enzyme evolution in Escherichia coli biomedcentral.com [HTML]S Light, P Kraulis - BMC bioinformatics, 2004 - biomedcentral.com http //scholar.google.com/scholar?q=related M0gfPqO-WsQJ scholar.google.com/ hl=ja as_sdt=2000 ... representation of metabolic pathways where the substrates and products are the vertices and the enzymes catalyzing the reactions are the edges (Figure 1). The type of network representation used in our study has been used before for metabolic network analysis where it has ... Metabolic network analysis on Phaffia rhodozyma yeast using 13C-labeled glucose and gas chromatography-mass spectrometry C Cannizzaro, B Christensen, J Nielsen, U … - Metabolic Engineering, 2004 - Elsevier http //scholar.google.com/scholar?q=related xVq5KkaMAd4J scholar.google.com/ hl=ja as_sdt=2000 Amino acid labeling patterns, as determined by GC–MS, were in accordance with a metabolic network consisting of the Embden–Meyerhof–Parnas pathway, the pentose phosphate pathway, and the TCA cycle. Glucose was mainly consumed along the pentose ... Metabolic network analysis integrated with transcript verification for sequenced genomes A Manichaikul, L Ghamsari, EFY Hom, C Lin, RR … - Nature methods, 2009 - nature.com http //scholar.google.com/scholar?q=related qlItzvkCLowJ scholar.google.com/ hl=ja as_sdt=2000 Present availability of genome sequences for diverse microorganisms brings opportunities for metabolic engineering through systems-level characterization of these organisms metabolic networks 1 . Such efforts require both functional and structural annotation of metabolic ... High-throughput metabolic flux analysis based on gas chromatography-mass spectrometry derived 13C constraints E Fischer, N Zamboni, U Sauer - Analytical biochemistry, 2004 - Elsevier http //scholar.google.com/scholar?q=related AGqwTbFzQbYJ scholar.google.com/ hl=ja as_sdt=2000 Influence of metabolic network structure and function on enzyme evolution biomedcentral.com [HTML]D Vitkup, P Kharchenko, A Wagner - Genome biology, 2006 - biomedcentral.com http //scholar.google.com/scholar?q=related tyk--z8xdr0J scholar.google.com/ hl=ja as_sdt=2000 ... Cold Spring Harbor Press, NY; 1982. OpenURL. Papp B, Pal C, Hurst LD Metabolic network analysis of the causes and evolution of the enzyme dispensability in yeast. Nature 2004,429 661-664. PubMed Abstract | Publisher Full Text OpenURL. ... Metabolomics-and proteomics-assisted genome annotation and analysis of the draft metabolic network of Chlamydomonas reinhardtii genetics.org [HTML]P May, S Wienkoop, S Kempa, B Usadel, N … - Genetics, 2008 - Genetics Soc America http //scholar.google.com/scholar?q=related lrqK6GwpxFIJ scholar.google.com/ hl=ja as_sdt=2000 ... Furthermore, the results will contribute to an improvement of metabolic databases. Presently, our methods are limited to one selected large-scale metabolic network analysis technique, the method of network expansion. Further ... Metabolic network analysis during fed-batch cultivation of Corynebacterium glutamicum for pantothenic acid production first quantitative data and analysis of by- … C Chassagnole, A Diano, F Létisse, ND Lindley - Journal of biotechnology, 2003 - Elsevier http //scholar.google.com/scholar?q=related CJC7H27nMvMJ scholar.google.com/ hl=ja as_sdt=2000 A first generation genetically modified strain of Corynebacterium glutamicum has been assessed for its potential to synthesise and accumulate the vitamin pantothenic acid in the medium using fed-batch cultivation technology, with biomass concentration controlled by isoleucine ... Metabolic modeling of microbial strains in silico ru.nl [PDF]MW Covert, CH Schilling, I Famili, JS Edwards, … - Trends in Biochemical …, 2001 - Elsevier http //scholar.google.com/scholar?q=related pjh6sWp3MRMJ scholar.google.com/ hl=ja as_sdt=2000 ... labeling experiments. Adv. Biochem. Eng. Biotechnol. 54, pp. 109–154. Christensen, B. and Nielsen, J., Metabolic network analysis. A powerful tool in metabolic engineering. Adv. Biochem. Eng. Biotechnol. 66, pp. 209–231. The ...
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- visitors Development of network-based pathway definitions the need to analyze real metabolic networks nhahocotton.org.vn [PDF]BO Palsson, ND Price, JA Papin - Update, 2003 - nhahocotton.org.vn http //scholar.google.com/scholar?q=related RJrIZTi52eQJ scholar.google.com/ hl=ja as_sdt=2000 ... A recent article [1] addresses the important issue of network-based metabolic pathway analysis. ... References 1 Klamt, S. and Stelling, J. (2003) Two approaches for metabolic pathway analysis? Trends Biotechnol. 21, 64–69 2 Karp, PD et al. ... PathFinder reconstruction and dynamic visualization of metabolic pathways oxfordjournals.org [PDF]A Goesmann, M Haubrock, F Meyer, J … - …, 2002 - Oxford Univ Press http //scholar.google.com/scholar?q=related tN609hXVn9QJ scholar.google.com/ hl=ja as_sdt=2000 ... database. Nucleic Acids Res., 26, 43–45. Tohsato,Y., Matsuda,H. and Hashimoto,A.(2000) A multiple align- ment algorithm for metabolic pathway analysis using enzyme hierarchy. Proceedings, ISMB 2000. pp. 376–383. Wackett ... Toward metabolic phenomics analysis of genomic data using flux balances dss.go.th [PDF]CH Schilling, JS Edwards, BO … - Biotechnology progress, 1999 - Wiley Online Library http //scholar.google.com/scholar?q=related 5xFNmiGLuFoJ scholar.google.com/ hl=ja as_sdt=2000 ... This approach of metabolic pathway analysis accompanied with FBA techniques can allow one to assess the basic structural capabilities and fitness of an organism as a result of the pathways that are theoretically present within the cell. ... Robustness Analysis of the Escherichiacoli Metabolic Network dss.go.th [PDF]JS Edwards, BO Palsson - Biotechnology Progress, 2000 - interscience.wiley.com http //scholar.google.com/scholar?q=related F73ImcZpznMJ scholar.google.com/ hl=ja as_sdt=2000 Page 1. Robustness Analysis of the Escherichia coli Metabolic Network Jeremy S.Edwards† and Bernhard O. Palsson* Department of Bioengineering, University of California-San Diego, La Jolla, California 92093-0412 Genomic ... FluxAnalyzer exploring structure, pathways, and flux distributions in metabolic networks on interactive flux maps oxfordjournals.org [PDF]S Klamt, J Stelling, M Ginkel, ED Gilles - Bioinformatics, 2003 - Oxford Univ Press http //scholar.google.com/scholar?q=related vOydM3d06iMJ scholar.google.com/ hl=ja as_sdt=2000 ... additionally reversibility and capacity restrictions for each reaction. Metabolic Pathway Analysis (MPA) searches for meaningful structural and functional units in metabolic networks. The two most promising, very similar ap- proaches ... Integrating cybernetic modeling with pathway analysis provides a dynamic, systems-level description of metabolic control JD Young, KL Henne, JA Morgan, AE … - Biotechnology and …, 2008 - interscience.wiley.com http //scholar.google.com/scholar?q=related SiQjLbrsCw4J scholar.google.com/ hl=ja as_sdt=2000 ... biochemical networks. Combining cybernetic control laws with concepts from metabolic pathway analysis has culminated in a sys- tematic strategy for constructing cybernetic models, which was previously lacking. The newly ... Exploring the pathway structure of metabolism decomposition into subnetworks and application to Mycoplasma pneumoniae oxfordjournals.org [PDF]S Schuster, T Pfeiffer, F Moldenhauer, I Koch, T … - …, 2002 - Oxford Univ Press http //scholar.google.com/scholar?q=related o1Qpi78HxmoJ scholar.google.com/ hl=ja as_sdt=2000 Page 1. BIOINFORMATICS Vol. 18 no. 2 2002 Pages 351–361 Exploring the pathway structure of metabolism decomposition into subnetworks and application to Mycoplasma pneumoniae S. Schuster 1 , T. Pfeiffer 2 , F. Moldenhauer 1 , I. Koch 3 and T. Dandekar 4, 5 ... The complete genome sequence of the gastric pathogen Helicobacter pylori JF Tomb, O White, AR Kerlavage, RA Clayton, GG … - Nature, 1997 - nature.com http //scholar.google.com/scholar?q=related Eo36dy8hFLcJ scholar.google.com/ hl=ja as_sdt=2000 ... Top of page Metabolism. Metabolic pathway analysis of the H. pylori genome suggests the following features. H. pylori uses glucose as the only source of carbohydrate and the main source for substrate-level phosphorylation. ... Deriving phylogenetic trees from the similarity analysis of metabolic pathways oxfordjournals.org [PDF]M Heymans, AK Singh - Bioinformatics, 2003 - Oxford Univ Press http //scholar.google.com/scholar?q=related Y2vvexN5fz8J scholar.google.com/ hl=ja as_sdt=2000 Page 1. BIOINFORMATICS Vol. 19 Suppl. 1 2003, pages i138–i146 DOI 10.1093/bioinformatics/btg1018 Deriving phylogenetic trees from the similarity analysis of metabolic pathways Maureen Heymans and Ambuj K. Singh ∗ ... Treatment of multifunctional enzymes in metabolic pathway analysis S Schuster, I Zevedei-Oancea - Biophysical chemistry, 2002 - Elsevier http //scholar.google.com/scholar?q=related G_O7SiZhvKsJ scholar.google.com/ hl=ja as_sdt=2000 In metabolic pathway analysis, it should be considered that many enzymes operate with low specificity (eg nucleoside diphosphokinase, uridine kinase, transketolase, aldolase), so that various substrates and products can be converted. Here, we analyze the effect of ...
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- visitors Metabolic pathway analysis of enzyme-deficient human red blood cells T ÇakIr, CS Tacer, KÖ Ülgen - Biosystems, 2004 - Elsevier http //scholar.google.com/scholar?q=related 8w1qIgoYqGcJ scholar.google.com/ hl=ja as_sdt=2000 Five enzymopathies (G6PDH, TPI, PGI, DPGM and PGK deficiencies) in the human red blood cells are investigated using a stoichiometric modeling approach, ie, metabolic pathway analysis. Elementary flux modes (EFMs) corresponding to each enzyme deficiency case ... Reconstruction of metabolic networks from genome data and analysis of their global structure for various organisms oxfordjournals.org [PDF]H Ma, AP Zeng - Bioinformatics, 2003 - Oxford Univ Press http //scholar.google.com/scholar?q=related SuHZgSLeNw8J scholar.google.com/ hl=ja as_sdt=2000 Page 1. BIOINFORMATICS Vol. 19 no. 2 2003 Pages 270–277 Reconstruction of metabolic networks from genome data and analysis of their global structure for various organisms Hongwu Ma1, 2 and An-Ping Zeng1,∗ 1GBF ... Elementary mode analysis a useful metabolic pathway analysis tool for characterizing cellular metabolism CT Trinh, A Wlaschin, F Srienc - Applied microbiology and biotechnology, 2009 - Springer http //scholar.google.com/scholar?q=related hkaWpJnxK5QJ scholar.google.com/ hl=ja as_sdt=2000 Abstract Elementary mode analysis is a useful metabolic pathway analysis tool to identify the structure of a metabolic network that links the cellular phenotype to the corresponding genotype. The analysis can decompose the intricate metabolic network comprised of ... Extreme pathway analysis of human red blood cell metabolism nih.gov [PDF]SJ Wiback, BO Palsson - Biophysical Journal, 2002 - Elsevier http //scholar.google.com/scholar?q=related hVaLEfzPgSEJ scholar.google.com/ hl=ja as_sdt=2000 Constraints-based models regulation of gene expression reduces the steady-state solution space MW Covert, BO Palsson - Journal of theoretical Biology, 2003 - Elsevier http //scholar.google.com/scholar?q=related o9VRtN2gAKQJ scholar.google.com/ hl=ja as_sdt=2000 ... Biol. 203, 249, 283. 26. CH SCHILLING, S. SCHUSTER, BO PALSSON and R.HEINRICH, Metabolic pathway analysis basic concepts and scientific applications in the post-genomic era. Biotechnol. Prog. 15 (1999), pp. 296–303. ... The JAK-STAT signaling network in the human B-cell an extreme signaling pathway analysis nih.gov [HTML]JA Papin, BO Palsson - Biophysical Journal, 2004 - Elsevier http //scholar.google.com/scholar?q=related myiNLachV-QJ scholar.google.com/ hl=ja as_sdt=2000 From genome to cellular phenotype—a role for metabolic flux analysis? A Cornish-Bowden, ML Cárdenas - Nature Biotechnology, 2000 - nature.com http //scholar.google.com/scholar?q=related Q1z877WO_uAJ scholar.google.com/ hl=ja as_sdt=2000 ... whether a bypass exists within a complex network. Metabolic pathway analysis aims to identify indispensable enzymes, thus predicting the effects of their deletion or inhibition. Flux analysis should also allow the determination ... On-line metabolic pathway analysis based on metabolic signal flow diagram H Shi, K Shimizu - Biotechnology and bioengineering, 1998 - interscience.wiley.com http //scholar.google.com/scholar?q=related wjDdrq_SGcQJ scholar.google.com/ hl=ja as_sdt=2000 Abstract In this work, an integrated modeling approach based on a metabolic signal flow diagram and cellular energetics was used to model the metabolic pathway analysis for the cultivation of yeast on glucose. This ap- proach enables us to make a clear analysis of the flow ... Metabolic pathway analysis of recombinant Saccharomyces cerevisiae with a galactose-inducible promoter based on a signal flow modeling approach S Jin, K Ye, K Shimizu - Journal of Fermentation and Bioengineering, 1995 - Elsevier http //scholar.google.com/scholar?q=related 0uzMsbsJrXEJ scholar.google.com/ hl=ja as_sdt=2000 The objective of this work was to develop a signal flow diagram-based modeling approach proposed by Endo et al. (1976) to organize the network of complex metabolic reactions occurring in the living cell, employing directed signal flow diagram in which the enzyme reaction ... Energy balance for analysis of complex metabolic networks nih.gov [PDF]DA Beard, S Liang, H Qian - Biophysical journal, 2002 - Elsevier http //scholar.google.com/scholar?q=related wcAvs5fp3FgJ scholar.google.com/ hl=ja as_sdt=2000
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- visitors Metabolic network analysis B Christensen, J Nielsen - Bioanalysis and biosensors for bioprocess …, 2000 - Springer http //scholar.google.com/scholar?q=related PiGOMNyMhjYJ scholar.google.com/ hl=ja as_sdt=2000 Metabolic network analysis is a tool for investigating the features that identify the topology of a metabolic network and the relative activities of its individual branches. The pillars of metabolic network analysis are mathematical modeling, allowing for a quantitative analysis, ... Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast B Papp, C Pál, LD Hurst - Nature, 2004 - nature.com http //scholar.google.com/scholar?q=related 0sM60oXJ2jQJ scholar.google.com/ hl=ja as_sdt=2000 Under laboratory conditions 80% of yeast genes seem not to be essential for viability 1 . This raises the question of what the mechanistic basis for dispensability is, and whether it is the result of selection for buffering or an incidental side product. Here we analyse these issues ... Genealogy profiling through strain improvement by using metabolic network analysis metabolic flux genealogy of several generations of lysine-producing … nih.gov [HTML]C Wittmann, E Heinzle - Applied and environmental microbiology, 2002 - Am Soc Microbiol http //scholar.google.com/scholar?q=related 49I4bRT2XYIJ scholar.google.com/ hl=ja as_sdt=2000 A comprehensive approach of metabolite balancing, 13 C tracer studies, gas chromatography-mass spectrometry, matrix-assisted laser desorption ionization-time of flight mass spectrometry, and isotopomer modeling was applied for comparative metabolic ... Metabolic network analysis of Penicillium chrysogenum using 13C-labeled glucose B Christensen, J Nielsen - Biotechnology and …, 2000 - interscience.wiley.com http //scholar.google.com/scholar?q=related 9XjgWNCKNqMJ scholar.google.com/ hl=ja as_sdt=2000 To provide a rational approach for directed genetic alter- ations in microorganisms, often referred to as metabolic engineering (Bailey, 1991; Stephanopoulos, 1999; Yarmush and Berthiaume, 1997), a detailed map of the fluxes in the central metabolism is an essential ... Metabolic network analysis of Bacillus clausii on minimal and semirich medium using 13C-labeled glucose T Christiansen, B Christensen, J Nielsen - Metabolic engineering, 2002 - Elsevier http //scholar.google.com/scholar?q=related GeX9jXLzh3EJ scholar.google.com/ hl=ja as_sdt=2000 Using 13 C-labeled glucose fed to the facultative alkalophilic Bacillus clausii producing the alkaline serine protease Savinase, the intracellular fluxes were quantified in continuous cultivation and in batch cultivation on a minimal medium. The flux through the pentose phosphate ... Genome-scale metabolic network analysis of the opportunistic pathogen Pseudomonas aeruginosa PAO1 nih.gov [HTML]MA Oberhardt, J Puchalka, KE Fryer, VAP … - Journal of …, 2008 - Am Soc Microbiol http //scholar.google.com/scholar?q=related isrhQUVHkSMJ scholar.google.com/ hl=ja as_sdt=2000 Pseudomonas aeruginosa is a major life-threatening opportunistic pathogen that commonly infects immunocompromised patients. This bacterium owes its success as a pathogen largely to its metabolic versatility and flexibility. A thorough understanding of P. aeruginosa s ... A metabolic network stoichiometry analysis of microbial growth and product formation WM Van Gulik, JJ Heijnen - Biotechnology and …, 1995 - interscience.wiley.com http //scholar.google.com/scholar?q=related p9UTGWFLJJUJ scholar.google.com/ hl=ja as_sdt=2000 ... Other work on metabolic network analysis using linear op- timization techniques has been performed on hybridoma cell Esehenchiu coli metabolism,3 .32 and acetate overflow in E. c01i.""~ Following the approach to solve underdetermined metabolic networks by conducting ... Metabolic network analysis of lysine producing Corynebacterium glutamicum at a miniaturized scale C Wittmann, HM Kim, E Heinzle - Biotechnology and …, 2004 - Wiley Online Library http //scholar.google.com/scholar?q=related B7ezo5R5OxIJ scholar.google.com/ hl=ja as_sdt=2000 Abstract We present a straightforward approach com- prising 13C tracer experiments at 200-AL volume in 96-well microtiter plates with on-line measurement of dissolved oxygen for quantitative high-throughput metabolic net- work analysis at a miniaturized scale. This ... Large-scale 13C-flux analysis reveals mechanistic principles of metabolic network robustness to null mutations in yeast biomedcentral.com [HTML]LM Blank, L Kuepfer, U Sauer - Genome Biology, 2005 - biomedcentral.com http //scholar.google.com/scholar?q=related TodhI8VNW54J scholar.google.com/ hl=ja as_sdt=2000
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- visitors In vivo analysis of intracellular amino acid labelings by GC/MS. C Wittmann, M Hans, E Heinzle - Analytical biochemistry, 2002 - mendeley.com ... TBDMS derivatization of amino acids is especially useful in metabolic network analysis, because M-57 fragments containing the entire carbon skeleton of the analyte can be observed by GC/MS with high signal intensities 8. The potential of the method is exemplified for ... Comparative metabolic flux analysis of lysine-producing Corynebacterium glutamicum cultured on glucose or fructose nih.gov [HTML]P Kiefer, E Heinzle, O Zelder, C … - Applied and …, 2004 - Am Soc Microbiol ... A comprehensive approach to 13 C tracer studies, labeling measurements by gas chromatography-mass spectrometry, metabolite balancing, and isotopomer modeling, was applied for comparative metabolic network analysis of lysine-producing Corynebacterium glutamicum ... It is all about metabolic fluxes nih.gov [HTML]J Nielsen - Journal of bacteriology, 2003 - Am Soc Microbiol http //scholar.google.com/scholar?q=related xAvLLrdbbNYJ scholar.google.com/ hl=ja as_sdt=2000 ... I. Experimental observations. Biotechnol. Bioeng. 55 305-316.[CrossRef] 21; Thykaer, J., B. Christensen, and J. Nielsen. 2002. Metabolic network analysis of an adipoyl-7-ADCA producing strain of Penicillium chrysogenum elucidation of adipate degradation.Metab. Eng. ... Using topology of the metabolic network to predict viability of mutant strains biomedcentral.com [PDF]Z Wunderlich, L Mirny - Genome Biology, 2005 - biomedcentral.com http //scholar.google.com/scholar?q=related sTavonuje7wJ scholar.google.com/ hl=ja as_sdt=2000 ... Ph.D. Thesis. University of Leeds; 1994. 14. Papp B, Pal C, Hurst LD Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast. Nature 2004, 429(6992) 661-664. 15. Jeong H, Tombor B, Albert R, Oltvai ZN, Barabasi AL The large-scale ... Novel proteins, putative membrane transporters, and an integrated metabolic network are revealed by quantitative proteomic analysis of Arabidopsis cell … plantphysiol.org [HTML]H Eubel, EH Meyer, NL Taylor, JD Bussell, N O … - Plant …, 2008 - Am Soc Plant Biol http //scholar.google.com/scholar?q=related aCgbR-dAtyMJ scholar.google.com/ hl=ja as_sdt=2000 ... This is aided by a metabolic network analysis that reveals a tight integration of functions and highlights specific metabolite nodes that most probably represent entry and exit metabolites that could require transport across the peroxisomal membrane. ... High-throughput phenomics experimental methods for mapping fluxomes bjmu.cn [PDF]U Sauer - Current opinion in Biotechnology, 2004 - Elsevier http //scholar.google.com/scholar?q=related XvhSxXXwbn4J scholar.google.com/ hl=ja as_sdt=2000 ... From its early days when material fluxes were balanced within assumed reaction networks [7.], metabolic network analysis [6. and 8.] has matured to actually identify the topology of active reactions and pathways and to quantify the molecular flux through them on a variety of ... Use of genome-scale microbial models for metabolic engineering KR Patil, M Åkesson, J Nielsen - Current opinion in biotechnology, 2004 - Elsevier http //scholar.google.com/scholar?q=related oAOz5SBTVHAJ scholar.google.com/ hl=ja as_sdt=2000 ... incorporate genome-scale biological data. Genome-scale stoichiometric models of microorganisms represent a first step in this direction. FBA, flux balance analysis; MFA, metabolic flux analysis; MNA, metabolic network analysis. ... Network identification and flux quantification in the central metabolism of Saccharomyces cerevisiae under different conditions of glucose repression nih.gov [HTML]AK Gombert, M Moreira dos Santos, B … - Journal of …, 2001 - Am Soc Microbiol http //scholar.google.com/scholar?q=related R5V_AodxCrwJ scholar.google.com/ hl=ja as_sdt=2000 ... flux estimates. The use of 13 C-labeled substrates enables both identification of the metabolic network structure and quantification of the metabolic fluxes and is therefore referred to as metabolic network analysis (5). This kind ... Metabolic flux analysis of Escherichia coli K12 grown on 13C-labeled acetate and glucose using GC-MS and powerful flux calculation method freelogy.org [PDF]J Zhao, K Shimizu - Journal of biotechnology, 2003 - Elsevier http //scholar.google.com/scholar?q=related w1m-5IKYKpsJ scholar.google.com/ hl=ja as_sdt=2000 Structural and functional analysis of cellular networks with CellNetAnalyzer biomedcentral.com [HTML]S Klamt, J Saez-Rodriguez, ED Gilles - BMC Systems Biology, 2007 - biomedcentral.com http //scholar.google.com/scholar?q=related bzwlVku0FL8J scholar.google.com/ hl=ja as_sdt=2000 ... CNA extends its predecessor FluxAnalyzer, originally developed for metabolic network analysis[7], by new methods for signalling and regulatory networks, ie for networks where signal flows are dominating (in contrast to mass flows in metabolic networks). ...
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Market Scenario The global Identity And Access Management Market has been expected to increase at a CAGR of 13.50%, with a value of USD 35.71 billion during the estimated forecasting year of 2030. The demand for identity and access management market is gaining traction due to the ring of regulatory compliances and security concerns. It also matters more than the increasing cloud adoption is one of the most important factors responsible for the growth of the identity and access management market sectors around the world. However, the integration of advanced technologies like blockchain as well as artificial intelligence into the identity and access management market solutions has been expected to raise the growth of the entire market sector within the upcoming time. It allows the organizations to manage the lifecycle of the identities like employees, contractors and vendors. Cloud technology is changing the way of business and other essential work while it is driven by cost efficiency and the economics of sale. Furthermore, the lack of effective security can undermine the benefits of cloud computing. This marks the fundamental need for security solutions that include security for identity-related crimes, and thus it drives the market for identity and access management. Secure the networks, and the digital assets have become an important component of every business. Hackers do not only commit the data breaches, but the individuals also commit many within an organization who have access to sensitive parts of the networks or facilities. Among these types of cloud deployment used in the market, the public cloud accounted for the largest share due to its increased adoption across the verticals. Due to the spread of the epidemic, the organizations have adopted remote work culture and cloud technology to mitigate the impact on the business operations. Request a Free Sample @ https //www.marketresearchfuture.com/sample_request/2635 Competitive Outlook The key participants identified by MRFR operating in the global identity access management market are– F5 Networks (U.S.), Amazon Web Services (U.S.), HP (U.S.), IBM (U.S.), Microsoft Inc. (U.S.), Oracle Corporation (U.S.), Siemens AG (Germany), Dell Inc. (U.S.), CA Technologies (U.S.), ForgeRock Inc. (U.S.) among others. Segmentation The global identity and access management market has been divided into solutions, deployment, organization size, end-user verticals and regional analysis. The solution section further divides the market into five parts identity cloud, identity governance, access management, directory services, and other solutions. The deployment section further divides the market into three parts on-premise, hybrid and cloud-based. As per the organization part, the entire market has been segmented into two categories large enterprises and small medium enterprises. The identity and access management market is further classified into eight sections BFSI, IT telecom, education, healthcare, retail, energy, manufacturing, and other end-user verticals with end-user verticals. As per the regional basis, the market is divided into five parts Asia-pacific, Europe, North America, South America, and Middle East Africa. Regional Analysis Over the last few times, several data breaches have been reported in the Northern American region. These breaches have affected several end-user segments ranging from IT and telecom, healthcare, to the energy sector. The data breach affected around 2.7 million people and 173,000 businesses. The leaked information includes names, addresses, birth dates, email addresses and information about the transaction habits. Besides this, the region s healthcare sector also can defend against the cyber threats that its employees seriously undermine. Industry News In Canada, the prevention of attacks on organizations, the IT budgets of the companies increased by 11% between 2014 and 2017. In the United States, the IT sector has spent on security solutions to reach USD 66 billion. Browse Full Report Details @ https //www.marketresearchfuture.com/reports/identity-access-management-market-2635 Table of Contents 1Executive Summary 2Scope of the Report 2.1Market Definition 2.2Scope of the Study 2.2.1Research objectives 2.2.2Assumptions Limitations 2.3Markets Structure Continued…. 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Research Analysis The market research report profiles well-balanced information with previous as well as future results with an aim to offer a better understanding of the Recycled Thermoplastic Market. The market report further offers an in-depth view of the leading factors that are related to increasing the demand growth for Recycled Thermoplastic Market. Not only this but also in this study the readers can get an in-depth report of the possibilities in combination with the latest trends in the targeted market. It is also a detailed combination of 10 years old qualitative and quantitative analysis of the industry that has been presented in the report with an aim to help the market players to increase maximum profit in the sector. The market research report also provides information on the record of individual sales records that are made with the expected revenue over the forecast period. This research report provides an extensive examination of all the related segments present in the industry. Moreover, it throws light on the recent development as well as the opportunity is that is going on in the Recycled Thermoplastic Market. Get a Sample PDF File@ https //www.quincemarketinsights.com/request-sample-88267?pu Market Report Features Overview Of The Market Report The market research report offers a detailed quantitative as well as qualitative overview of the market for Recycled Thermoplastic Market on the basis of area, category, product, competitors, and application. In terms of expanded coverage, the market report is further extended in terms of end-user market analysis and the comprehensive producer profile. Market Segmentation Of Recycled Thermoplastic Market Market The market segmentation of the Recycled Thermoplastic Market is done on the basis of technology, product type, application, distribution channel, and end-user. Geographical segmentation is also being done to get valuable insights into the Recycled Thermoplastic Market. Geographical Analysis Doing the geographical analysis is very important to know about the broad feature of the market. In this section, the readers can get a comprehensive analysis of the Recycled Thermoplastic Market based on the geographical location. This section throws light on the demand and sales output for the Recycled Thermoplastic Market at the national and international levels. The study is being done taking into account some of the major geographic regions such as North America, Europe, Asia Pacific, South America, Middle East, and Africa. Make an Enquiry for purchasing this Report @ https //www.quincemarketinsights.com/enquiry-before-buying/enquiry-before-buying-88267?pu Market Key Highlights The market report on the Recycled Thermoplastic Market is a summary of the current market situation for the Recycled Thermoplastic Market. Moreover, the analysis provides information regarding the newly launched product and also the products that are to be launched during the forecast period. The study also includes minute details regarding market share, segment, trends, growth and forecast W Plastics, Plastipak Holdings, Inc., PARC Corporation, Clear Path Recycling, B. Schoenberg and Co., Custom Polymers Inc., RJM International Inc., Suez SA, Merlin Plastics Alberta Inc., Ricova International Inc. Quince Market Insights Top Trending Research Report* https //qmi189135117.wordpress.com/2022/09/16/cumene-sulfonic-acid-market-size-industry-growth-rate-global-share-upcoming-trends-leading-players-products-and-services-overview-forecast-to-2032/ https //qmi189135117.wordpress.com/2022/09/16/3-hexenyl-salicylate-market-key-findings-growth-prospects-and-size-by-country-top-manufacturer-expansion-plans-and-business-strategy-forecast-to-2032/ https //qmi189135117.wordpress.com/2022/09/16/ethylene-glycol-monostearate-market-trends-growth-size-swot-analysis-opportunity-assessment-by-forecast-to-2021-drivers-and-applications-are-pertinent-for-sustenance-during-the-forecast-period-20/ Details Contained In The Recycled Thermoplastic Market Report 2021 Market Overview 1.1 Market Introduction 1.2 Market Analysis By Type 1.2.1 Type 1 1.2.2 Type 2 1.3 Market Analysis By Applications 1.3.1 Application 1 1.3.2 Application 2 1.4 Market Analysis by Regions 1.4.1 North America 1.4.2 Europe 1.4.3 Asia Pacific 1.4.4 South America 1.4.5 the Middle East and Africa Market Scope Market Segmentation by type, application, end-users and regions Market Size estimation Market Competition Key Market Leaders Conclusions The market research report offers a detailed study of the Recycled Thermoplastic Market which include market shares, size and growth opportunities by applications, product types and geographic regions. Not only this but also the report also contains a detailed summary of the leading market players. The experts have also mentioned the market growth, threats, opportunities and risks. About Us QMI has the most comprehensive collection of market research products and services available on the web. We deliver reports from virtually all major publications and refresh our list regularly to provide you with immediate online access to the world’s most extensive and up-to-date archive of professional insights into global markets, companies, goods, and patterns. Contact us Quince Market Insights Phone +1 208 405 2835 Email sales@quincemarketinsights.com Website https //www.quincemarketinsights.com/